BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 2031

Title: Secondary Structure and Topology of Human Interleukin 4 in Solution

Authors: Redfield, Christina; Smith, Lorna; Boyd, Jonathan; Lawrence, G.; Edwards, Robert; Smith, Richard; Dobson, Christopher

Citation: Redfield, Christina; Smith, Lorna; Boyd, Jonathan; Lawrence, G.; Edwards, Robert; Smith, Richard; Dobson, Christopher. "Secondary Structure and Topology of Human Interleukin 4 in Solution"  Biochemistry 30, 11029-11035 (1991).

Assembly members:
interleukin 4, polymer, 130 residues, Formula weight is not available

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: not available   Host organism: Escherichia coli

Entity Sequences (FASTA):
interleukin 4: MHKCDITLQEIIKTLNSLTE QKTLCTELTVTDIFAASKNT TEKETFCRAATVLXQFYSHH EKDTRCLGATAQQFHRHKQL IRFLKRLDRNLWGLAGLNSC PVKEANQSTLENFLERLKTI MREKYSKCSS

Data sets:
Data typeCount
15N chemical shifts138
1H chemical shifts686

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1interleukin 41

Entities:

Entity 1, interleukin 4 130 residues - Formula weight is not available

1   METHISLYSCYSASPILETHRLEUGLNGLU
2   ILEILELYSTHRLEUASNSERLEUTHRGLU
3   GLNLYSTHRLEUCYSTHRGLULEUTHRVAL
4   THRASPILEPHEALAALASERLYSASNTHR
5   THRGLULYSGLUTHRPHECYSARGALAALA
6   THRVALLEUXGLNPHETYRSERHISHIS
7   GLULYSASPTHRARGCYSLEUGLYALATHR
8   ALAGLNGLNPHEHISARGHISLYSGLNLEU
9   ILEARGPHELEULYSARGLEUASPARGASN
10   LEUTRPGLYLEUALAGLYLEUASNSERCYS
11   PROVALLYSGLUALAASNGLNSERTHRLEU
12   GLUASNPHELEUGLUARGLEULYSTHRILE
13   METARGGLULYSTYRSERLYSCYSSERSER

Samples:

sample_one:

sample_condition_set_one: pH: 5.3 na; temperature: 308 K

Experiments:

NameSampleSample stateSample conditions
not availablesample_onenot availablesample_condition_set_one

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Related Database Links:

BMRB 4094
PDB
EMBL CAA34682 CAP72493
GB AAA59149 AAA59150 AAH66277 AAH67514 AAH67515
REF NP_000580 NP_001011714 XP_002815914 XP_003829346 XP_004042527
SP P05112 P79339 Q8HYB1