BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 4283

Title: NMR Structure of the Angiogenesis Marker Oncofoetal Fibronectin ED-B Domain

Authors: Fattorusso, Roberto; Pellecchia, Maurizio; Viti, Francesca; Neri, Paolo; Neri, Dario; Wuthrich, Kurt

Citation: Fattorusso, Roberto; Pellecchia, Maurizio; Viti, Francesca; Neri, Paolo; Neri, Dario; Wuthrich, Kurt. "NMR Structure of the Angiogenesis Marker Oncofoetal Fibronectin ED-B Domain"  Structure 7, 381-390 (1999).

Assembly members:
fibronectin extra domain B, polymer, 95 residues, 10000 Da.

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
fibronectin extra domain B: MRGSEVPQLTDLSFVDITDS SIGLRWTPLNSSTIIGYRIT VVAAGEGIPIFEDFVDSSVG YYTVTGLEPGIDYDISVITL INGGESAPTTLTQQT

Data sets:
Data typeCount
1H chemical shifts657
15N chemical shifts97

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1EDB1

Entities:

Entity 1, EDB 95 residues - 10000 Da.

1   METARGGLYSERGLUVALPROGLNLEUTHR
2   ASPLEUSERPHEVALASPILETHRASPSER
3   SERILEGLYLEUARGTRPTHRPROLEUASN
4   SERSERTHRILEILEGLYTYRARGILETHR
5   VALVALALAALAGLYGLUGLYILEPROILE
6   PHEGLUASPPHEVALASPSERSERVALGLY
7   TYRTYRTHRVALTHRGLYLEUGLUPROGLY
8   ILEASPTYRASPILESERVALILETHRLEU
9   ILEASNGLYGLYGLUSERALAPROTHRTHR
10   LEUTHRGLNGLNTHR

Samples:

sample_one: fibronectin extra domain B 1.3 mM; NaCl 40 mM; phosphate_buffer 20 mM; H2O 90%; D2O 10%

sample_two: fibronectin extra domain B 1.3 mM; NaCl 40 mM; phosphate_buffer 20 mM; D2O 100%

sample_conditions_one: pH: 7.5

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 500 MHz
  • Bruker DRX 600 MHz
  • Bruker DRX 750 MHz

Related Database Links:

BMRB 19906
PDB
EMBL CAB52437
GB AAA52461 AAA67749