BMRB Entry 6698

Title:
The structured core of a largely unstructured protein, malarial merozoite surface protein 2 (MSP2), is amyloidogenic
Deposition date:
2005-06-21
Original release date:
2008-10-27
Authors:
Keizer, David; Adda, Christopher; Murphy, Vince; Rizkalla, Michael; Jackson, David; Anders, Robin; Norton, Raymond
Citation:

Citation: Yang, X.; Adda, Christopher; Keizer, David; Murphy, Vince; Rizkalla, M.; Perugini, M.; Jackson, David; Anders, Robin; Norton, Raymond. "A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils"  J. Pept. Sci. 13, 839-848 (2007).
PubMed: 17883245

Assembly members:

Assembly members:
MSP2 N-terminal region, polymer, 25 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Plasmodium falciparum   Taxonomy ID: 5833   Superkingdom: Eukaryota   Kingdom: not available   Genus/species: Plasmodium falciparum

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
MSP2 N-terminal region: IKNESKYSNTFINNAYNMSI RRSMA

Data sets:
Data typeCount
1H chemical shifts145

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1MSP2 peptide1

Entities:

Entity 1, MSP2 peptide 25 residues - Formula weight is not available

1   ILELYSASNGLUSERLYSTYRSERASNTHR
2   PHEILEASNASNALATYRASNMETSERILE
3   ARGARGSERMETALA

Samples:

sample_1: MSP2 N-terminal region nM

conditions_1: pH: 3.4

Experiments:

NameSampleSample stateSample conditions
not availablenot availablenot availablenot available

Software:

No software information available

NMR spectrometers:

  • Bruker DRX 600 MHz
  • Bruker Avance 500 MHz

Related Database Links:

BMRB 15075 15590 25202
PDB
EMBL CAA37829 CAA37830 CAA53701 CAA53946 CAA60699
GB AAA19735 AAA19737 AAA19738 AAA19739 AAA19740
PIR B45632 C39112
PRF 2023165A 2023165B
REF XP_001349578
SP P19260 P19599 P50496 P50497 P50498
AlphaFold P19260 P19599 P50496 P50497 P50498