BMRB Entry 16857

Title:
Human Jagged-1, exon 6
Deposition date:
2010-04-13
Original release date:
2010-05-19
Authors:
Pintar, Alessandro; Guarnaccia, Corrado; Pongor, Sandor
Citation:

Citation: Pintar, Alessandro; Guarnaccia, Corrado; Dhir, Somdutta; Pongor, Sandor. "Exon 6 of human JAG1 encodes a conserved structural unit."  BMC Struct. Biol. 9, 43-43 (2009).
PubMed: 19586525

Assembly members:

Assembly members:
Exon 6 of human Jagged-1, polymer, 44 residues, 5048.796 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Exon 6 of human Jagged-1: RCQYGWQGLYCDKCIPHPGC VHGICNEPWQCLCETNWGGQ LCDK

Data sets:
Data typeCount
1H chemical shifts288

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1JAG11

Entities:

Entity 1, JAG1 44 residues - 5048.796 Da.

Experimentally determined disulfide bonds: 2-11; 14-25; 20-31; 33-42

1   ARGCYSGLNTYRGLYTRPGLNGLYLEUTYR
2   CYSASPLYSCYSILEPROHISPROGLYCYS
3   VALHISGLYILECYSASNGLUPROTRPGLN
4   CYSLEUCYSGLUTHRASNTRPGLYGLYGLN
5   LEUCYSASPLYS

Samples:

sample_1: JAG1 0.5 mM; H2O 90%; D2O 10%

sample_2: JAG1 0.5 mM; D2O 100%

sample_conditions_1: pH: 4.5; pressure: 1 atm; temperature: 298 K

sample_conditions_2: pH: 4.5; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H COSYsample_2isotropicsample_conditions_2
2D 1H-1H TOCSYsample_2isotropicsample_conditions_2
2D 1H-1H NOESYsample_2isotropicsample_conditions_2

Software:

CYANA v2.1, G ntert P. - refinement

NMR spectrometers:

  • Bruker Avance 800 MHz

Related Database Links:

PDB
DBJ BAE23235 BAG35596 BAG63823
GB AAB06509 AAB39007 AAB84053 AAC51323 AAC51731
REF NP_000205 NP_001178107 NP_038850 NP_062020 XP_001116216
SP P78504 Q63722 Q9QXX0
TPG DAA23668
AlphaFold P78504 Q63722 Q9QXX0