Biological Magnetic Resonance Data Bank

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 20121

Title: Tubulysin conformation bound to tubulin   PubMed: 20496362

Authors: Kubicek, Karel; Grimm, Steffen; Orts, Julien; Sasse, Florenz; Carlomagno, Teresa

Citation: Kubicek, Karel; Grimm, S. Kaspar; Orts, Julien; Sasse, Florenz; Carlomagno, Teresa. "The tubulin-bound structure of the antimitotic drug tubulysin."  Angew. Chem. Int. Ed. Engl. 49, 4809-4812 (2010).

Assembly members:
tubulysin, polymer, 4 residues, 841 Da.

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
tubulysin: XIXX

Data sets:
Data typeCount
1H chemical shifts56

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all


Entity Assembly IDEntity NameEntity ID


Entity 1, tubulysin 4 residues - 841 Da.



sample_1: tubulysin 0.5 mM; tubulin 0.01 mM; sodium phosphate 1.5 mM; calcium phosphate 1.5 mM; H2O 95%; DMSO 5%

sample_conditions_1: temperature: 298 K; pH: 7.0


NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicsample_conditions_1


X-PLOR_NIH v2.31, Schwieters, Kuszewski, Tjandra and Clore - structure solution

NMR spectrometers:

  • Bruker Avance 900 MHz

Related Database Links: