BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 4642

Title: SOLUTION STRUCTURE OF HUMAN BETA-DEFENSIN-2   PubMed: 11300761

Authors: Sawai, M.; Jia, H.; Liu, L.; Aseyev, V.; Wiencek, J.; McCray, P.; Ganz, T.; Kearney, W.; Tack, B.

Citation: Sawai, M.; Jia, H.; Liu, L.; Aseyev, V.; Wiencek, J.; McCray, P.; Ganz, T.; Kearney, W.; Tack, B.. "The NMR Structure of Human Beta-Defensin-2 Reveals a Novel Alpha-Helical Segment "  Biochemistry 40, 3810-3816 (2001).

Assembly members:
HUMAN BETA-DEFENSIN-2, polymer, 41 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: .

Entity Sequences (FASTA):
HUMAN BETA-DEFENSIN-2: GIGDPVTCLKSGAICHPVFC PRRYKQIGTCGLPGTKCCKK P

Data sets:
Data typeCount
1H chemical shifts285

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1BETA-DEFENSIN-21

Entities:

Entity 1, BETA-DEFENSIN-2 41 residues - Formula weight is not available

1   GLYILEGLYASPPROVALTHRCYSLEULYS
2   SERGLYALAILECYSHISPROVALPHECYS
3   PROARGARGTYRLYSGLNILEGLYTHRCYS
4   GLYLEUPROGLYTHRLYSCYSCYSLYSLYS
5   PRO

Samples:

sample_1: HUMAN BETA-DEFENSIN-2 0.87 mM; sodium phosphate buffer 45 mM; H2O 90%; D2O 10%

sample_cond_1: pH: 3.74; temperature: 298 K; ionic strength: 0.045 M; pressure: 1.013 atm

Experiments:

NameSampleSample stateSample conditions
2D NOESYsample_1not availablesample_cond_1
DOF-COSYsample_1not availablesample_cond_1
TOCSYsample_1not availablesample_cond_1

Software:

DYANA v1.5 - structure solution

NMR spectrometers:

  • Varian INOVA 500 MHz

Related Database Links:

PDB
EMBL CAA95992 CAB65126 CCD28567
GB AAC33549 AAC69554 AAF20154 AAH69285 AAH93983
REF NP_001009076 NP_001027999 NP_001192195 NP_004933
SP O15263 Q9BDS9 Q9TT12