BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 4779

Title: Backbone sequential resonance assignments of the ligand binding domain of the human TGF-beta type II receptor

Authors: Hinck, Andrew

Citation: Hinck, Andrew; Walker, Kerfoot; Martin, Nathan; Deep, Shashank; Hinck, Cynthia; Freedberg, Daron. "Letter to the Editor: Sequential resonance assignments of the extracellular ligand binding domain of the human TGF-b type II receptor"  J. Biomol. NMR 18, 369-370 (2000).

Assembly members:
TGF-bet type II receptor, polymer, 122 residues, 13783.6 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
TGF-bet type II receptor: VTDNAGAVKFPQLCKFCDVR FSTCDNQKSCMSNCSITSIC EKPQEVCVAVWRKNDENITL ETVCHDPKLPYHDFILEDAA SPKCIMKEKKKPGETFFMCS CSSDECNDNIIFSEEYNTSN PD

Data sets:
Data typeCount
1H chemical shifts677
13C chemical shifts477
15N chemical shifts105

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1TbR21

Entities:

Entity 1, TbR2 122 residues - 13783.6 Da.

1   VALTHRASPASNALAGLYALAVALLYSPHE
2   PROGLNLEUCYSLYSPHECYSASPVALARG
3   PHESERTHRCYSASPASNGLNLYSSERCYS
4   METSERASNCYSSERILETHRSERILECYS
5   GLULYSPROGLNGLUVALCYSVALALAVAL
6   TRPARGLYSASNASPGLUASNILETHRLEU
7   GLUTHRVALCYSHISASPPROLYSLEUPRO
8   TYRHISASPPHEILELEUGLUASPALAALA
9   SERPROLYSCYSILEMETLYSGLULYSLYS
10   LYSPROGLYGLUTHRPHEPHEMETCYSSER
11   CYSSERSERASPGLUCYSASNASPASNILE
12   ILEPHESERGLUGLUTYRASNTHRSERASN
13   PROASP

Samples:

sample1: TGF-bet type II receptor, [U-99% 13C; U-99% 15N], 0.5 – 2.0 mM

condition1: pH: 5.50; temperature: 300 K; ionic strength: 0.05 M

Experiments:

NameSampleSample stateSample conditions
1H-15N HSQCnot availablenot availablenot available
CBCA(CO)NHnot availablenot availablenot available
HNCACBnot availablenot availablenot available
HNCOnot availablenot availablenot available
HN(CA)COnot availablenot availablenot available
HBHA(CO)NHnot availablenot availablenot available
H(CO)NHnot availablenot availablenot available
C(CO)NHnot availablenot availablenot available
HCCH-TOCSYnot availablenot availablenot available

Software:

nmrPipe vFeb, 2000 -

NMR spectrometers:

  • Bruker AMX2 500 MHz

Related Database Links:

REF XP_001095987 XP_001095763 XP_001095877 NP_001020018 NP_003233
SWISS-PROT P37173
GenBank AAI52841 AAQ02596 AAB17553 AAB40916 AAA61164
DBJ BAG62117 BAG10803 BAG36796 BAA05673 BAA09332
PDB
BMRB 5953 5954