BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 5136

Title: Solution structure of lactam analogue (EDap (Ace)IWGESGKLI(DAB)TTA) of HIV gp41 600-612 loop   PubMed: 12381305

Authors: Phan Chan Du, Angelique; Limal, David; Semetey, Vincent; Dali, Hayet; Jolivet, Michel; Desgranges, Claude; Cung, Manh Thong; Briand, Jean Paul; Petit, Marie Christine; Muller, Sylviane

Citation: Du, Angelique; Limal, David; Semetey, Vincent; Dali, Hayet; Jolivet, Michel; Desgranges, Claude; Cung, Manh; Briand, Jean; Petit, Marie; Muller, Sylviane. "Structural and Immunological Characterization of Heteroclitic Peptide Analogues Corresponding to the 600-612 Region of the HIV Envelope gp41 Glycoprotein"  J. Mol. Biol. 323, 503-521 (2002).

Assembly members:
EDap (Ace)IWGESGKLI(DAB)TTA analogue of HIV GP41, polymer, 14 residues, Formula weight is not available

Natural source:   Common Name: HIV   Taxonomy ID: 12721   Superkingdom: Virus   Kingdom: not available   Genus/species: Lentivirus human immunodeficiency virus

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
EDap (Ace)IWGESGKLI(DAB)TTA analogue of HIV GP41: XIWGESGKLIXTTA

Data sets:
Data typeCount
1H chemical shifts86

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1EDap (Ace)IWGESGKLI(DAB)TTA analogue of HIV GP411

Entities:

Entity 1, EDap (Ace)IWGESGKLI(DAB)TTA analogue of HIV GP41 14 residues - Formula weight is not available

1   ACEILETRPGLYGLUSERGLYLYSLEUILE
2   DABTHRTHRALA

Samples:

sample_1: EDap (Ace)IWGESGKLI(DAB)TTA analogue of HIV GP41 3 mM; DMSO, [U-2H], 100%

sample_cond_1: pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
TOCSYsample_1not availablesample_cond_1
DQF-COSYsample_1not availablesample_cond_1
2D NOESYsample_1not availablesample_cond_1

Software:

xwinnmr v2.6 - collection, processing

XEASY v1.2 - data analysis

DYANA v1.5 - refinement

DISCOVER v3 - refinement

NMR spectrometers:

  • Bruker AVANCE 600 MHz

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