BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 5502

Title: Solution Structure of Hepcidin-20   PubMed: 12138110

Authors: Hunter, H.; Fulton, D.; Ganz, T.; Vogel, H.

Citation: Hunter, H.; Fulton, D.; Ganz, T.; Vogel, H.. "The Solution Structure of Human Hepcidin, a Peptide Hormone with Antimicrobial Activity that is Involved in Iron Uptake and Hereditary Hemochromatosis"  J. Biol. Chem. 277, 37597-37603 (2002).

Assembly members:
hepicidin, polymer, 20 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
hepicidin: ICIFCCGCCHRSKCGMCCKT

Data sets:
Data typeCount
1H chemical shifts123

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Hepcidin-201

Entities:

Entity 1, Hepcidin-20 20 residues - Formula weight is not available

1   ILECYSILEPHECYSCYSGLYCYSCYSHIS
2   ARGSERLYSCYSGLYMETCYSCYSLYSTHR

Samples:

sample_1: hepicidin 0.78 mM; H2O 90%; D2O 10%

sample_cond_1: pH: 3.2; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D NOESYnot availablenot availablenot available
2D TOCSYnot availablenot availablenot available
13C-HSQCnot availablenot availablenot available
Diffusion experimentnot availablenot availablenot available

Software:

xwinnmr v2.6 - collection

CNS v1.1 - structure solution

NMRPipe v3.4 - processing

NMR spectrometers:

  • Bruker AVANCE 700 MHz

Related Database Links:

BMRB 5501
PDB
EMBL CAC09419
GB AAG23966 AAH20612 AAK14912 AAQ89032 ABF47098
REF NP_001103163 NP_066998 XP_003280066 XP_003280067 XP_003816224
SP P81172