BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 5713

Title: Influence of pH on NMR structure and stability of the human prion protein globular domain

Authors: Calzolai, Luigi; Zahn, Ralph

Citation: Calzolai, Luigi; Zahn, Ralph. "Influence of pH on NMR structure and stability of the human prion protein globular domain"  J. Biol. Chem. ., .-..

Assembly members:
human prion protein, polymer, 112 residues, Formula weight is not available

Natural source:   Common Name: HUMAN   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
human prion protein: GSVVGGLGGYMLGSAMSRPI IHFGSDYEDRYYRENMHRYP NQVYYRPMDEYSNQNNFVHD CVNITIKQHTVTTTTKGENF TETDVKMMERVVEQMCITQY ERESQAYYQRGS

Data sets:
Data typeCount
13C chemical shifts351
15N chemical shifts126
1H chemical shifts763

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1hPrP1

Entities:

Entity 1, hPrP 112 residues - Formula weight is not available

1   GLYSERVALVALGLYGLYLEUGLYGLYTYR
2   METLEUGLYSERALAMETSERARGPROILE
3   ILEHISPHEGLYSERASPTYRGLUASPARG
4   TYRTYRARGGLUASNMETHISARGTYRPRO
5   ASNGLNVALTYRTYRARGPROMETASPGLU
6   TYRSERASNGLNASNASNPHEVALHISASP
7   CYSVALASNILETHRILELYSGLNHISTHR
8   VALTHRTHRTHRTHRLYSGLYGLUASNPHE
9   THRGLUTHRASPVALLYSMETMETGLUARG
10   VALVALGLUGLNMETCYSILETHRGLNTYR
11   GLUARGGLUSERGLNALATYRTYRGLNARG
12   GLYSER

Samples:

sample_1: human prion protein0.8 – 1.3 mM

Ex-cond1: pH: 7.0; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
not availablesample_1not availableEx-cond1

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Related Database Links:

BMRB 15676 16743 17714 17756 17757 17780 18426 18550 19268 4379 4402 4434 4620 4641 4736 5378
PDB
DBJ BAA00011 BAF62360 BAG32276 BAG32277 BAG32278
EMBL CAA58442 CAG46836 CAG46869
GB AAA19664 AAA60182 AAA68632 AAA68633 AAB59442
REF NP_000302 NP_001009093 NP_001073590 NP_001073591 NP_001073592
SP P04156 P40252 P61766 P61767 P61768