BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 5940

Title: 1H, 15N and 13C backbone assignment of the carboxyl terminal domain of the cytokine binding module of the interleukin-6 receptor (IL-6R)

Authors: Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Rose-John, Stefan; Grotzinger, Joachim

Citation: Schwantner, Andreas; Dingley, Andrew; Ozbek, Suat; Hecht, Oliver; Rose-John, Stefan; Grotzinger, Joachim. "Letter to the Editor: 1H, 15N, 13C Backbone Assignment of the Carboxyl Terminal Domain of the Cytokine Binding Module of the Interleukin-6 Receptor"  J. Biomol. NMR 29, 407-408 (2004).

Assembly members:
interleukin-6 receptor, polymer, 126 residues, 14500 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
interleukin-6 receptor: MGILQPDPPANITVTAVARN PRWLSVTWQDPHSWNSSFYR LRFELRYRAERSKTFTTWMV KDLQHHCVIHDAWSGLRHVV QLRAQEEFGQGEWSEWSPEA MGTPWTESRSPPAENEVSTP MQALTT

Data sets:
Data typeCount
1H chemical shifts360
13C chemical shifts393
15N chemical shifts103

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1interleukin-6 receptor1

Entities:

Entity 1, interleukin-6 receptor 126 residues - 14500 Da.

1   METGLYILELEUGLNPROASPPROPROALA
2   ASNILETHRVALTHRALAVALALAARGASN
3   PROARGTRPLEUSERVALTHRTRPGLNASP
4   PROHISSERTRPASNSERSERPHETYRARG
5   LEUARGPHEGLULEUARGTYRARGALAGLU
6   ARGSERLYSTHRPHETHRTHRTRPMETVAL
7   LYSASPLEUGLNHISHISCYSVALILEHIS
8   ASPALATRPSERGLYLEUARGHISVALVAL
9   GLNLEUARGALAGLNGLUGLUPHEGLYGLN
10   GLYGLUTRPSERGLUTRPSERPROGLUALA
11   METGLYTHRPROTRPTHRGLUSERARGSER
12   PROPROALAGLUASNGLUVALSERTHRPRO
13   METGLNALALEUTHRTHR

Samples:

sample_1: interleukin-6 receptor, [U-95% 13C; U-90% 15N], 1.0 mM

condition_1: pH: 5.0; temperature: 293 K

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • Varian INOVA 600 MHz

Related Database Links:

PDB
DBJ BAD97302 BAF85702 BAG35601 BAI46031
EMBL CAA31312 CAA41231
GB AAH89410 AAI32685 AAI32687 AAX36842 ABK41906
PRF 1502360A
REF NP_000556 NP_852004 XP_001114404 XP_002810148 XP_003308452
SP P08887