BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 6020

Title: Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I   PubMed: 15134657

Authors: Powers, Jon-Paul; Rozek, Annett; Hancock, Robert

Citation: Powers, Jon-Paul; Rozek, Annett; Hancock, Robert. "Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I"  Biochim. Biophys. Acta 1698, 239-250 (2004).

Assembly members:
Polyphemusin I, polymer, 19 residues, Formula weight is not available
NH2, non-polymer, 16.023 Da.

Natural source:   Common Name: Horseshoe crab   Taxonomy ID: 61202   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Tachypleus polyphemus

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
Polyphemusin I: RRWCFRVCYRGFCYRKCRX

Data sets:
Data typeCount
1H chemical shifts139

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1polyphemusin I1

Entities:

Entity 1, polyphemusin I 19 residues - Formula weight is not available

1   ARGARGTRPCYSPHEARGVALCYSTYRARG
2   GLYPHECYSTYRARGLYSCYSARGNH2

Samples:

sample_1: Polyphemusin I 2 mM

Condition_1: pH: 4.0; temperature: 300 K

Experiments:

NameSampleSample stateSample conditions
1H NOESYsample_1not availableCondition_1
1H TOCSYsample_1not availableCondition_1
1H DQF-COSYsample_1not availableCondition_1

Software:

NMRView v5.0.3 - Integration of NOESY peak volumes.

X-PLOR NIH v2.9.0 - Distance geometry simulated annealing

NMR spectrometers:

  • Varian INOVA 600 MHz

Related Database Links:

PDB
SP P14215