BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 6070

Title: Solution Structure of Endothelin-1 with its C-terminal Folding   PubMed: 15070353

Authors: Takashima, Hiroyuki; Mimura, Norio; Ohkubo, Tadayasu; Yoshida, Takuya; Tamaoki, Haruhiko; Kobayashi, Yuji

Citation: Takashima, Hiroyuki; Mimura, Norio; Ohkubo, Tadayasu; Yoshida, Takuya; Tamaoki, Haruhiko; Kobayashi, Yuji. "Distributed Computing and NMR Constraint-Based High-Resolution Structure Determination, Applied for Bioactive Peptide Endothelin-1 to Determine C-terminal Folding"  J. Am. Chem. Soc. 124, 4504-4505 (2004).

Assembly members:
Endothelin-1, polymer, 21 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
Endothelin-1: CSCSSLMDKECVYFCHLDII W

Data sets:
Data typeCount
1H chemical shifts137

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1ET-11

Entities:

Entity 1, ET-1 21 residues - Formula weight is not available

1   CYSSERCYSSERSERLEUMETASPLYSGLU
2   CYSVALTYRPHECYSHISLEUASPILEILE
3   TRP

Samples:

sample_1: Endothelin-1 2.5 mM; acetic acid 5%

sample_cond_1: pH: 3; temperature: 297.7 K; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D NOESYnot availablenot availablenot available
DQF-COSYnot availablenot availablenot available
2D TOCSYnot availablenot availablenot available

Software:

XPLOR-NIH v2.0.6 - structure solution, refinement

NMR spectrometers:

  • Bruker AMX 600 MHz

Related Database Links:

BMRB 1503 1728 1867 193 194 2262 2263
PDB
DBJ BAA07830 BAA11109 BAB86360 BAC30702 BAD02920
EMBL CAA30296 CAA36954 CAA37117 CAA42555 CAA68718
GB AAA41129 AAA52338 AAA52339 AAA52407 AAA97608
PRF 1405327A 1904245A 2206384A
REF NP_001002956 NP_001009810 NP_001090567 NP_001095166 NP_001121271
SP P05305 P09558 P13206 P17322 P22387
TPG DAA16084