BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 4437

Title: Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1

Authors: MORGAN, W.; BIRDSALL, B.; FRENKIEL, T.; GRADWELL, M.; BURGHAUS, P.; SYED, S.; UTHAIPIBULL, C.; HOLDER, A.; FEENEY, J.

Citation: MORGAN, W.; BIRDSALL, B.; FRENKIEL, T.; GRADWELL, M.; BURGHAUS, P.; SYED, S.; UTHAIPIBULL, C.; HOLDER, A.; FEENEY, J.. "Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1 "  J. Mol. Biol. 289, 113-122 (1999).

Assembly members:
MEROZOITE SURFACE PROTEIN 1, polymer, 96 residues, 11604 Da.

Natural source:   Common Name: malaria parasite P. falciparum   Taxonomy ID: 5833   Superkingdom: Eukaryota   Kingdom: not available   Genus/species: PLASMODIUM FALCIPARUM

Experimental source:   Production method: recombinant technology   Host organism: PICHIA(KOMAGATAELLA) PASTORIS

Entity Sequences (FASTA):
MEROZOITE SURFACE PROTEIN 1: NISQHQCVKKQCPQNSGCFR HLDEREECKCLLNYKQEGDK CVENPNPTCNENNGGCDADA KCTEEDSGSNGKKITCECTK PDSYPLFDGIFCSSSN

Data sets:
Data typeCount
1H chemical shifts607
13C chemical shifts339
15N chemical shifts105

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1MSP-11

Entities:

Entity 1, MSP-1 96 residues - 11604 Da.

1   ASNILESERGLNHISGLNCYSVALLYSLYS
2   GLNCYSPROGLNASNSERGLYCYSPHEARG
3   HISLEUASPGLUARGGLUGLUCYSLYSCYS
4   LEULEUASNTYRLYSGLNGLUGLYASPLYS
5   CYSVALGLUASNPROASNPROTHRCYSASN
6   GLUASNASNGLYGLYCYSASPALAASPALA
7   LYSCYSTHRGLUGLUASPSERGLYSERASN
8   GLYLYSLYSILETHRCYSGLUCYSTHRLYS
9   PROASPSERTYRPROLEUPHEASPGLYILE
10   PHECYSSERSERSERASN

Samples:

sample_1: MEROZOITE SURFACE PROTEIN 12.1 – 2.6 mM

sample_cond_1: pH: 6.5; temperature: 298 K; ionic strength: 0.35 M; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D-NOESYnot availablenot availablenot available
2D-ROESYnot availablenot availablenot available
3D-[15N]NOESY-HSQCnot availablenot availablenot available
3D-{15N]ROESY-HSQCnot availablenot availablenot available
3D-[13C]HMQC-NOESYnot availablenot availablenot available
4D-[13C]HMQC-NOESY-[13C]HSQCnot availablenot availablenot available
4D-[13C]HMQC-NOESY-[15N]HSQCnot availablenot availablenot available
2D-DQF-COSYnot availablenot availablenot available
3D-HNHAnot availablenot availablenot available
3D-HNHBnot availablenot availablenot available
3D-HN(C0)HBnot availablenot availablenot available
2D-[15N][13Cgamma]-SPINECHO-HSQCnot availablenot availablenot available
2D-[13C'][13Cgamma]-SPINECHO-HSQCnot availablenot availablenot available
3D-LRCHnot availablenot availablenot available
2D-TOCSYnot availablenot availablenot available
2D-[15N]HSQCnot availablenot availablenot available
2D-[13C]HSQCnot availablenot availablenot available
3D-[15N]-TOCSY-HSQCnot availablenot availablenot available
3D-HCCH-TOCSYnot availablenot availablenot available
3D-CBCA(CO)NHnot availablenot availablenot available
3D-CBCANHnot availablenot availablenot available
3D-HNCOnot availablenot availablenot available

Software:

No software information available

NMR spectrometers:

  • Varian Unity 600 MHz
  • Varian Unity-Plus 500 MHz

Related Database Links:

PDB
DBJ BAA02605 BAA02607 BAA02609 BAA02610 BAA02611
EMBL CAA26676 CAA27070 CAA27446 CAA33163 CAA71607
GB AAA29611 AAA29709 AAA62217 AAA62218 AAA62219
SP P04932 P04933 P04934 P19598 P50495