BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 6924

Title: 1H chemical shifts for discrepin, a scorpion toxin that blocks IA currents of the voltage dependent K+ channels   PubMed: 16460026

Authors: Prochnicka-Chalufour, Ada; Corzo, Gerardo; Satake, Honoo; Martin-Euaclaire, Marie-France; Murgia, Anna; Prestipino, Gianfranco; D'Suze, Gina; Possani, Lourival; Delepierre, Muriel

Citation: Prochnicka-Chalufour, Ada; Corzo, Gerardo; Satake, Honoo; Martin-Eauclaire, Marie-France; Murgia, Anna; Prestipino, Gianfranco; D'Suze, Gina; Possani, Lourival; Delepierre, Muriel. "Solution Structure of Discrepin, a New K(+)-Channel Blocking Peptide from the alpha-KTx15 Subfamily(,)."  Biochemistry 45, 1795-1804 (2006).

Assembly members:
discrepin, Tityus discrepans toxin from alpha-KTx15 sub-family, polymer, 38 residues, Formula weight is not available

Natural source:   Common Name: scorpion   Taxonomy ID: 57059   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Tityus discrepans

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
discrepin, Tityus discrepans toxin from alpha-KTx15 sub-family: XIDTNVKCSGSSKCVKICID RYNTRGAKCINGRCTCYP

Data sets:
Data typeCount
1H chemical shifts250

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1discrepin1

Entities:

Entity 1, discrepin 38 residues - Formula weight is not available

the first residue of the sequence (Z in 1 letter code) is a pyroglutamic acid PCA.

1   PCAILEASPTHRASNVALLYSCYSSERGLY
2   SERSERLYSCYSVALLYSILECYSILEASP
3   ARGTYRASNTHRARGGLYALALYSCYSILE
4   ASNGLYARGCYSTHRCYSTYRPRO

Samples:

sample_1: discrepin 3.0 mM; H20 90%; D20 10%

conditions_1: pH: 3; temperature: 308 K

Experiments:

NameSampleSample stateSample conditions
DQF-COSYsample_1not availableconditions_1
TOCSYsample_1not availableconditions_1
NOESYsample_1not availableconditions_1

Software:

VNMR v6.1C -

XEASY v1.2 -

NMR spectrometers:

  • Varian Inova 600 MHz

Related Database Links:

PDB
EMBL CAY61912
SP P84777