data_7154 ####################### # Entry information # ####################### save_entry_information _Saveframe_category entry_information _Entry_title ; NMR spectroscopy of T4 Lysozyme peptide fragments ; _BMRB_accession_number 7154 _BMRB_flat_file_name bmr7154.str _Entry_type original _Submission_date 2006-06-07 _Accession_date 2006-06-07 _Entry_origination author _NMR_STAR_version 2.1.1 _Experimental_method NMR _Details . loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Najbar L. V. . 2 Craik D. J. . 3 Wade J. D. . 4 McLeish M. J. . stop_ loop_ _Saveframe_category_type _Saveframe_category_type_count assigned_chemical_shifts 1 stop_ loop_ _Data_type _Data_type_count "1H chemical shifts" 83 "1N chemical shifts" 2 stop_ loop_ _Revision_date _Revision_keyword _Revision_author _Revision_detail 2008-11-12 original author . stop_ _Original_release_date 2008-11-12 save_ ############################# # Citation for this entry # ############################# save_entry_citation _Saveframe_category entry_citation _Citation_full . _Citation_title 'Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments' _Citation_status published _Citation_type journal _CAS_abstract_code . _MEDLINE_UI_code . _PubMed_ID 10801343 loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Najbar L. V. . 2 Craik D. J. . 3 Wade J. D. . 4 McLeish M. J. . stop_ _Journal_abbreviation Biochemistry _Journal_volume 39 _Journal_issue 19 _Journal_CSD . _Book_chapter_title . _Book_volume . _Book_series . _Book_ISBN . _Conference_state_province . _Conference_abstract_number . _Page_first 5911 _Page_last 5920 _Year 2000 _Details . save_ ################################## # Molecular system description # ################################## save_assembly _Saveframe_category molecular_system _Mol_system_name 'HELIX E' _Enzyme_commission_number . loop_ _Mol_system_component_name _Mol_label 'fragment corresponding to Lys Helix E (residues 92-107)' $HELIX_E stop_ _System_molecular_weight . _System_physical_state unfolded _System_oligomer_state ? _System_paramagnetic no _System_thiol_state 'not present' _Database_query_date . _Details . save_ ######################## # Monomeric polymers # ######################## save_HELIX_E _Saveframe_category monomeric_polymer _Mol_type polymer _Mol_polymer_class protein _Name_common 'helix E (lys 92-107)' _Molecular_mass . _Mol_thiol_state 'not present' _Details . ############################## # Polymer residue sequence # ############################## _Residue_count 16 _Mol_residue_sequence DAVRRAALINMVFQMG loop_ _Residue_seq_code _Residue_author_seq_code _Residue_label 1 92 ASP 2 93 ALA 3 94 VAL 4 95 ARG 5 96 ARG 6 97 ALA 7 98 ALA 8 99 LEU 9 100 ILE 10 101 ASN 11 102 MET 12 103 VAL 13 104 PHE 14 105 GLN 15 106 MET 16 107 GLY stop_ _Sequence_homology_query_date . _Sequence_homology_query_revised_last_date 2015-01-28 loop_ _Database_name _Database_accession_code _Database_entry_mol_name _Sequence_query_to_submitted_percentage _Sequence_subject_length _Sequence_identity _Sequence_positive _Sequence_homology_expectation_value PDB 102L "How Amino-Acid Insertions Are Allowed In An Alpha-Helix Of T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 103L "How Amino-Acid Insertions Are Allowed In An Alpha-Helix Of T4 Lysozyme" 100.00 167 100.00 100.00 1.31e+00 PDB 104L "How Amino-Acid Insertions Are Allowed In An Alpha-Helix Of T4 Lysozyme" 100.00 166 100.00 100.00 5.65e-01 PDB 107L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.88e-01 PDB 108L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 109L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 110L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.64e-01 PDB 111L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.82e-01 PDB 112L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 113L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.82e-01 PDB 114L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.53e-01 PDB 115L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 118L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 119L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 120L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 122L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 123L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 126L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.15e+00 PDB 127L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.15e+00 PDB 128L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.15e+00 PDB 130L "Structures Of Randomly Generated Mutants Of T4 Lysozyme Show That Protein Stability Can Be Enhanced By Relaxation Of Strain And" 100.00 164 100.00 100.00 5.58e-01 PDB 131L "Structures Of Randomly Generated Mutants Of T4 Lysozyme Show That Protein Stability Can Be Enhanced By Relaxation Of Strain And" 100.00 164 100.00 100.00 5.58e-01 PDB 137L "Structural Basis Of Amino Acid Alpha Helix Propensity" 100.00 164 100.00 100.00 5.88e-01 PDB 140L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.47e-01 PDB 141L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.53e-01 PDB 142L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.25e-01 PDB 143L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.53e-01 PDB 144L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 1.26e+00 PDB 145L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.47e-01 PDB 146L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.41e-01 PDB 147L "Role Of Backbone Flexibility In The Accommodation Of Variants That Repack The Core Of T4 Lysozyme" 100.00 164 100.00 100.00 5.53e-01 PDB 148L "A Covalent Enzyme-Substrate Intermediate With Saccharide Distortion In A Mutant T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 155L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.94e-01 PDB 156L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.53e-01 PDB 157L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.64e-01 PDB 158L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.53e-01 PDB 159L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.30e-01 PDB 160L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 1.23e+00 PDB 161L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.53e-01 PDB 162L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.53e-01 PDB 163L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.53e-01 PDB 164L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.41e-01 PDB 165L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.76e-01 PDB 166L "Control Of Enzyme Activity By An Engineered Disulfide Bond" 100.00 164 100.00 100.00 5.76e-01 PDB 171L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 5.64e-01 PDB 174L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 6.66e-01 PDB 176L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 177L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 8.98e-01 PDB 178L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 8.98e-01 PDB 180L "Protein Flexibility And Adaptability Seen In 25 Crystal Forms Of T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 192L "A Helix Initiation Signal In T4 Lysozyme Identified By Polyalanine Mutagenesis" 100.00 164 100.00 100.00 5.76e-01 PDB 195L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 1.27e+00 PDB 196L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 5.64e-01 PDB 197L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 5.47e-01 PDB 198L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 5.58e-01 PDB 199L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 5.64e-01 PDB 1B6I "T4 Lysozyme Mutant With Cys 54 Replaced By Thr, Cys 97 Replaced By Ala, Thr 21 Replaced By Cys And Lys 124 Replaced By Cys (C54" 100.00 164 100.00 100.00 6.59e-01 PDB 1C60 "T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM Argon" 100.00 164 100.00 100.00 5.25e-01 PDB 1C61 "T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM Krypton" 100.00 164 100.00 100.00 5.25e-01 PDB 1C62 "T4 Lysozyme Mutant C54tC97AF153A IN THE PRESENCE OF 8 ATM Xenon" 100.00 164 100.00 100.00 5.25e-01 PDB 1C63 "T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM Argon" 100.00 164 100.00 100.00 5.47e-01 PDB 1C64 "T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM Krypton" 100.00 164 100.00 100.00 5.47e-01 PDB 1C65 "T4 Lysozyme Mutant C54tC97AL121A IN THE PRESENCE OF 8 ATM Xenon" 100.00 164 100.00 100.00 5.47e-01 PDB 1C66 "T4 Lysozyme Mutant C54tC97AL121AL133A IN THE PRESENCE OF 8 Atm Argon" 100.00 164 100.00 100.00 5.47e-01 PDB 1C67 "T4 Lysozyme Mutant C54tC97AL121AL133A IN THE PRESENCE OF 8 Atm Krypton" 100.00 164 100.00 100.00 5.47e-01 PDB 1C68 "T4 Lysozyme Mutant C54tC97AL121AL133A IN THE PRESENCE OF 8 Atm Xenon" 100.00 164 100.00 100.00 5.47e-01 PDB 1C6P "T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM ARGON" 100.00 164 100.00 100.00 5.58e-01 PDB 1C6Q "T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM Krypton" 100.00 164 100.00 100.00 5.58e-01 PDB 1C6T "T4 Lysozyme Mutant C54tC97A IN THE PRESENCE OF 8 ATM XENON" 100.00 164 100.00 100.00 5.58e-01 PDB 1CTW "T4 Lysozyme Mutant I78a" 100.00 164 100.00 100.00 5.36e-01 PDB 1CU0 "T4 Lysozyme Mutant I78m" 100.00 164 100.00 100.00 5.53e-01 PDB 1CU2 "T4 Lysozyme Mutant L84m" 100.00 164 100.00 100.00 5.64e-01 PDB 1CU3 "T4 Lysozyme Mutant V87m" 100.00 164 100.00 100.00 5.53e-01 PDB 1CU5 "T4 Lysozyme Mutant L91m" 100.00 164 100.00 100.00 5.64e-01 PDB 1CU6 "T4 Lysozyme Mutant L91a" 100.00 164 100.00 100.00 5.47e-01 PDB 1CV1 "T4 Lysozyme Mutant V111m" 100.00 164 100.00 100.00 5.53e-01 PDB 1CV3 "T4 Lysozyme Mutant L121m" 100.00 164 100.00 100.00 5.64e-01 PDB 1CV4 "T4 Lysozyme Mutant L118m" 100.00 164 100.00 100.00 5.64e-01 PDB 1CV5 "T4 Lysozyme Mutant L133m" 100.00 164 100.00 100.00 5.64e-01 PDB 1CV6 "T4 Lysozyme Mutant V149m" 100.00 164 100.00 100.00 5.53e-01 PDB 1CVK "T4 Lysozyme Mutant L118a" 100.00 164 100.00 100.00 5.47e-01 PDB 1D2W "N-Terminal Domain Core Methionine Mutation" 100.00 164 100.00 100.00 5.53e-01 PDB 1D2Y "N-Terminal Domain Core Methionine Mutation" 100.00 164 100.00 100.00 5.53e-01 PDB 1D3F "N-Terminal Domain Core Methionine Mutation" 100.00 164 100.00 100.00 5.53e-01 PDB 1D3J "N-Terminal Domain Core Methionine Mutation" 100.00 164 100.00 100.00 5.64e-01 PDB 1EPY "T4 Lysozyme Mutant, T21hC54TC97AQ141HT142H" 100.00 164 100.00 100.00 1.03e+00 PDB 1G06 "Crystal Structure Of T4 Lysozyme Mutant V149s" 100.00 164 100.00 100.00 1.20e+00 PDB 1G07 "Crystal Structure Of T4 Lysozyme Mutant V149c" 100.00 164 100.00 100.00 1.06e+00 PDB 1G0G "Crystal Structure Of T4 Lysozyme Mutant T152a" 100.00 164 100.00 100.00 5.76e-01 PDB 1G0J "Crystal Structure Of T4 Lysozyme Mutant T152s" 100.00 164 100.00 100.00 5.58e-01 PDB 1G0K "Crystal Structure Of T4 Lysozyme Mutant T152c" 100.00 164 100.00 100.00 5.82e-01 PDB 1G0L "Crystal Structure Of T4 Lysozyme Mutant T152v" 100.00 164 100.00 100.00 5.70e-01 PDB 1G0M "Crystal Structure Of T4 Lysozyme Mutant T152i" 100.00 164 100.00 100.00 5.64e-01 PDB 1G0P "Crystal Structure Of T4 Lysozyme Mutant V149g" 100.00 164 100.00 100.00 1.23e+00 PDB 1G0Q "Crystal Structure Of T4 Lysozyme Mutant V149i" 100.00 164 100.00 100.00 1.31e+00 PDB 1G1V "T4 Lysozyme Mutant C54tC97AI58T" 100.00 164 100.00 100.00 1.20e+00 PDB 1JQU "Are Carboxy Terminii Of Helices Coded By The Local Sequence Or By Tertiary Structure Contacts" 100.00 164 100.00 100.00 5.47e-01 PDB 1JTM "Alternative Structures Of A Sequence Extended T4 Lysozyme Show That The Highly Conserved Beta-Sheet Has Weak Intrinsic Folding " 100.00 178 100.00 100.00 7.89e-01 PDB 1JTN "Alternative Structures Of A Sequence Extended T4 Lysozyme Show That The Highly Conserved Beta-Sheet Region Has Weak Intrinsic F" 100.00 178 100.00 100.00 7.89e-01 PDB 1KNI "Stabilizing Disulfide Bridge Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 6.59e-01 PDB 1KS3 "Methionine Core Mutant Of T4 Lysozyme" 100.00 162 100.00 100.00 5.56e-01 PDB 1L35 "Structure Of A Thermostable Disulfide-Bridge Mutant Of Phage T4 Lysozyme Shows That An Engineered Crosslink In A Flexible Regio" 100.00 164 100.00 100.00 9.07e-01 PDB 1L39 "Contributions Of Engineered Surface Salt Bridges To The Stability Of T4 Lysozyme Determined By Directed Mutagenesis" 100.00 164 100.00 100.00 1.23e+00 PDB 1L40 "Contributions Of Engineered Surface Salt Bridges To The Stability Of T4 Lysozyme Determined By Directed Mutagenesis" 100.00 164 100.00 100.00 1.23e+00 PDB 1L41 "Contributions Of Engineered Surface Salt Bridges To The Stability Of T4 Lysozyme Determined By Directed Mutagenesis" 100.00 164 100.00 100.00 5.58e-01 PDB 1L59 "Analysis Of The Interaction Between Charged Side Chains And The Alpha-Helix Dipole Using Designed Thermostable Mutants Of Phage" 100.00 164 100.00 100.00 5.82e-01 PDB 1L61 "Analysis Of The Interaction Between Charged Side Chains And The Alpha-Helix Dipole Using Designed Thermostable Mutants Of Phage" 100.00 164 100.00 100.00 5.82e-01 PDB 1L62 "Analysis Of The Interaction Between Charged Side Chains And The Alpha-Helix Dipole Using Designed Thermostable Mutants Of Phage" 100.00 164 100.00 100.00 5.82e-01 PDB 1L63 "Analysis Of The Interaction Between Charged Side Chains And The Alpha-Helix Dipole Using Designed Thermostable Mutants Of Phage" 100.00 164 100.00 100.00 5.58e-01 PDB 1L64 "Tolerance Of T4 Lysozyme To Multiple Xaa (Right Arrow) Ala Substitutions: A Polyalanine Alpha-Helix Containing Ten Consecutive " 100.00 164 100.00 100.00 6.06e-01 PDB 1L65 "Tolerance Of T4 Lysozyme To Multiple Xaa (Right Arrow) Ala Substitutions: A Polyalanine Alpha-Helix Containing Ten Consecutive " 100.00 164 100.00 100.00 5.47e-01 PDB 1L66 "Tolerance Of T4 Lysozyme To Multiple Xaa (Right Arrow) Ala Substitutions: A Polyalanine Alpha-Helix Containing Ten Consecutive " 100.00 164 100.00 100.00 5.70e-01 PDB 1L67 "Tolerance Of T4 Lysozyme To Multiple Xaa (Right Arrow) Ala Substitutions: A Polyalanine Alpha-Helix Containing Ten Consecutive " 100.00 164 100.00 100.00 5.47e-01 PDB 1L68 "Tolerance Of T4 Lysozyme To Multiple Xaa (Right Arrow) Ala Substitutions: A Polyalanine Alpha-Helix Containing Ten Consecutive " 100.00 164 100.00 100.00 5.76e-01 PDB 1L76 "Tolerance Of T4 Lysozyme To Proline Substitutions Within The Long Interdomain Alpha-Helix Illustrates The Adaptability Of Prote" 100.00 164 100.00 100.00 1.13e+00 PDB 1L85 "Similar Hydrophobic Replacements Of Leu 99 And Phe 153 Within The Core Of T4 Lysozyme Have Different Structural And Thermodynam" 100.00 164 100.00 100.00 5.25e-01 PDB 1L86 "Similar Hydrophobic Replacements Of Leu 99 And Phe 153 Within The Core Of T4 Lysozyme Have Different Structural And Thermodynam" 100.00 164 100.00 100.00 1.40e+00 PDB 1L87 "Similar Hydrophobic Replacements Of Leu 99 And Phe 153 Within The Core Of T4 Lysozyme Have Different Structural And Thermodynam" 100.00 164 100.00 100.00 1.38e+00 PDB 1L88 "Similar Hydrophobic Replacements Of Leu 99 And Phe 153 Within The Core Of T4 Lysozyme Have Different Structural And Thermodynam" 100.00 164 100.00 100.00 5.47e-01 PDB 1L95 "Similar Hydrophobic Replacements Of Leu 99 And Phe 153 Within The Core Of T4 Lysozyme Have Different Structural And Thermodynam" 100.00 164 100.00 100.00 5.25e-01 PDB 1LLH "Are Carboxy Terminii Of Helices Coded By The Local Sequence Or By Tertiary Structure Contacts" 100.00 164 100.00 100.00 5.64e-01 PDB 1LW9 "Multiple Methionine Substitutions Are Tolerated In T4 Lysozyme And Have Coupled Effects On Folding And Stability" 100.00 164 100.00 100.00 5.58e-01 PDB 1LYE "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.70e-01 PDB 1LYF "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.58e-01 PDB 1LYG "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.82e-01 PDB 1LYH "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.88e-01 PDB 1LYI "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.82e-01 PDB 1LYJ "Dissection Of Helix Capping In T4 Lysozyme By Structural And Thermodynamic Analysis Of Six Amino Acid Substitutions At Thr 59" 100.00 164 100.00 100.00 5.76e-01 PDB 1OYU "Long-Distance Conformational Changes In A Protein Engineered By Modulated Sequence Duplication" 100.00 175 100.00 100.00 1.37e+00 PDB 1P2L "T4 Lysozyme Core Repacking Mutant V87iTA" 100.00 164 100.00 100.00 1.31e+00 PDB 1P2R "T4 Lysozyme Core Repacking Mutant I78vTA" 100.00 164 100.00 100.00 5.53e-01 PDB 1P56 "Duplication-Extension Of Helix A Of T4 Lysozyme" 100.00 176 100.00 100.00 6.73e-01 PDB 1P5C "Circular Permutation Of Helix A In T4 Lysozyme" 100.00 167 100.00 100.00 5.66e-01 PDB 1P64 "T4 Lysozyme Core Repacking Mutant L133fTA" 100.00 164 100.00 100.00 5.82e-01 PDB 1P6Y "T4 Lysozyme Core Repacking Mutant M120y/ta" 100.00 164 100.00 100.00 9.55e-01 PDB 1PQI "T4 Lysozyme Core Repacking Mutant I118lCORE7TA" 100.00 164 100.00 100.00 5.88e-01 PDB 1PQK "Repacking Of The Core Of T4 Lysozyme By Automated Design" 100.00 164 100.00 100.00 5.64e-01 PDB 1PQM "T4 Lysozyme Core Repacking Mutant V149iT152VTA" 100.00 164 100.00 100.00 5.64e-01 PDB 1PQO "T4 Lysozyme Core Repacking Mutant L118iTA" 100.00 164 100.00 100.00 5.58e-01 PDB 1QT3 "T26d Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 5.82e-01 PDB 1QT4 "T26q Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 5.82e-01 PDB 1QT5 "D20e Mutant Structure Of T4 Lysozyme" 100.00 164 100.00 100.00 1.27e+00 PDB 1QT6 "E11h Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 5.64e-01 PDB 1QT7 "E11n Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 1QT8 "T26h Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 1QTB "The Introduction Of Strain And Its Effects On The Structure And Stability Of T4 Lysozyme" 100.00 162 100.00 100.00 5.34e-01 PDB 1QTC "The Introduction Of Strain And Its Effects On The Structure And Stability Of T4 Lysozyme" 100.00 162 100.00 100.00 5.39e-01 PDB 1QTD "The Introduction Of Strain And Its Effects On The Structure And Stability Of T4 Lysozyme" 100.00 162 100.00 100.00 9.33e-01 PDB 1QTV "T26e Apo Structure Of T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 1QTZ "D20c Mutant Of T4 Lysozyme" 100.00 164 100.00 100.00 1.20e+00 PDB 1QUG "E108v Mutant Of T4 Lysozyme" 100.00 162 100.00 100.00 5.39e-01 PDB 1SSW "Crystal Structure Of Phage T4 Lysozyme Mutant Y24aY25AT26AI27AC54TC97A" 100.00 164 100.00 100.00 5.53e-01 PDB 1SSY "Crystal Structure Of Phage T4 Lysozyme Mutant G28aI29AG30AC54TC97A" 100.00 164 100.00 100.00 5.19e-01 PDB 1T8A "Use Of Sequence Duplication To Engineer A Ligand-Triggered Long-Distance Molecular Switch In T4 Lysosyme" 100.00 175 100.00 100.00 1.61e+00 PDB 1T8F "Crystal Structure Of Phage T4 Lysozyme Mutant R14aK16AI17AK19AT21AE22AC54TC97A" 100.00 164 100.00 100.00 5.88e-01 PDB 1T8G "Crystal Structure Of Phage T4 Lysozyme Mutant L32aL33AT34AC54TC97AE108V" 100.00 164 100.00 100.00 5.58e-01 PDB 1T97 "Use Of Sequence Duplication To Engineer A Ligand-Triggered Long-Distance Molecular Switch In T4 Lysosyme" 100.00 175 100.00 100.00 1.61e+00 PDB 1TLA "Hydrophobic Core Repacking And Aromatic-Aromatic Interaction In The Thermostable Mutant Of T4 Lysozyme Ser 117 (Right Arrow) Ph" 100.00 164 100.00 100.00 5.88e-01 PDB 1ZUR "Crystal Structure Of Spin Labeled T4 Lysozyme (V131r1f)" 100.00 164 100.00 100.00 1.06e+00 PDB 1ZWN "Crystal Structure Of Spin Labeled T4 Lysozyme (V131r1b)" 100.00 164 100.00 100.00 1.06e+00 PDB 1ZYT "Crystal Structure Of Spin Labeled T4 Lysozyme (A82r1)" 100.00 164 100.00 100.00 1.05e+00 PDB 200L 'Thermodynamic And Structural Compensation In "size-Switch" Core-Repacking Variants Of T4 Lysozyme' 100.00 164 100.00 100.00 5.47e-01 PDB 201L "How Amino-Acid Insertions Are Allowed In An Alpha-Helix Of T4 Lysozyme" 100.00 166 100.00 100.00 9.76e-01 PDB 205L "How Amino-Acid Insertions Are Allowed In An Alpha-Helix Of T4 Lysozyme" 100.00 167 100.00 100.00 5.84e-01 PDB 206L "Phage T4 Lysozyme" 100.00 164 100.00 100.00 1.13e+00 PDB 209L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 167 100.00 100.00 5.84e-01 PDB 210L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 163 100.00 100.00 1.22e+00 PDB 211L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 212L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 168 100.00 100.00 5.72e-01 PDB 213L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 214L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 215L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 216L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 217L "Structural Basis Of Alpha-Helix Propensity At Two Sites In T4 Lysozyme" 100.00 164 100.00 100.00 5.70e-01 PDB 218L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 165 100.00 100.00 5.65e-01 PDB 219L "Protein Structure Plasticity Exemplified By Insertion And Deletion Mutants In T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 221L "The Energetic Cost And The Structural Consequences Of Burying A Hydroxyl Group Within The Core Of A Protein Determined From Ala" 100.00 164 100.00 100.00 1.13e+00 PDB 230L "T4 Lysozyme Mutant M6l" 100.00 164 100.00 100.00 1.11e+00 PDB 232L "T4 Lysozyme Mutant M120k" 100.00 164 100.00 100.00 1.05e+00 PDB 233L "T4 Lysozyme Mutant M120l" 100.00 164 100.00 100.00 1.11e+00 PDB 235L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.58e-01 PDB 236L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.58e-01 PDB 237L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.58e-01 PDB 239L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 240L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 241L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 242L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 243L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 245L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 1.23e+00 PDB 246L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.25e-01 PDB 247L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.47e-01 PDB 248L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 249L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 250L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.36e-01 PDB 251L "The Response Of T4 Lysozyme To Large-To-Small Substitutions Within The Core And Its Relation To The Hydrophobic Effect" 100.00 164 100.00 100.00 5.47e-01 PDB 253L Lysozyme 100.00 164 100.00 100.00 5.47e-01 PDB 254L Lysozyme 100.00 164 100.00 100.00 1.31e+00 PDB 255L Hydrolase 100.00 164 100.00 100.00 5.53e-01 PDB 257L "An Adaptable Metal-Binding Site Engineered Into T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 258L "An Adaptable Metal-Binding Site Engineered Into T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 259L "An Adaptable Metal-Binding Site Engineered Into T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 260L "An Adaptable Metal-Binding Site Engineered Into T4 Lysozyme" 100.00 164 100.00 100.00 5.76e-01 PDB 261L "Structural Characterisation Of An Engineered Tandem Repeat Contrasts The Importance Of Context And Sequence In Protein Folding" 100.00 173 100.00 100.00 1.55e+00 PDB 262L "Structural Characterisation Of An Engineered Tandem Repeat Contrasts The Importance Of Context And Sequence In Protein Folding" 100.00 173 100.00 100.00 1.55e+00 PDB 2A4T "Crystal Structure Of Spin Labeled T4 Lysozyme (V131r7)" 100.00 164 100.00 100.00 1.06e+00 PDB 2B7X "Sequential Reorganization Of Beta-Sheet Topology By Insertion Of A Single Strand" 100.00 170 100.00 100.00 1.20e+00 PDB 2CUU "Crystal Structure Of Spin Labeled T4 Lysozyme (v131r1)" 100.00 164 100.00 100.00 1.06e+00 PDB 2F2Q "High Resolution Crystal Strcuture Of T4 Lysosyme Mutant L20r63A LIGANDED TO GUANIDINIUM ION" 100.00 175 100.00 100.00 1.61e+00 PDB 2F32 "Xray Crystal Structure Of Lysozyme Mutant L20R63A LIGANDED To Ethylguanidinium" 100.00 175 100.00 100.00 1.61e+00 PDB 2F47 "Xray Crystal Structure Of T4 Lysozyme Mutant L20R63A Liganded To Methylguanidinium" 100.00 175 100.00 100.00 1.61e+00 PDB 2HUK "Crystal Structure Of T4 Lysozyme V131c Synthetic Dimer" 100.00 164 100.00 100.00 1.06e+00 PDB 2HUL "Crystal Structure Of T4 Lysozyme S44c Synthetic Dimer" 100.00 164 100.00 100.00 5.88e-01 PDB 2HUM "Crystal Structure Of T4 Lysozyme D72c Synthetic Dimer" 100.00 164 100.00 100.00 1.20e+00 PDB 2IGC "Structure Of Spin Labeled T4 Lysozyme Mutant T115r1a" 100.00 164 100.00 100.00 5.82e-01 PDB 2L78 "Design And Structural Analysis Of Alternative Hydrophobic Core Packing Arrangements In Bacteriophage T4 Lysozyme" 100.00 164 100.00 100.00 1.31e+00 PDB 2NTG "Structure Of Spin-Labeled T4 Lysozyme Mutant T115r7" 100.00 164 100.00 100.00 5.82e-01 PDB 2NTH "Structure Of Spin-Labeled T4 Lysozyme Mutant L118r1" 100.00 164 100.00 100.00 1.10e+00 PDB 2O4W "T4 Lysozyme Circular Permutant" 100.00 171 100.00 100.00 6.28e-01 PDB 2O79 "T4 Lysozyme With C-Terminal Extension" 100.00 170 100.00 100.00 5.97e-01 PDB 2O7A "T4 Lysozyme C-Terminal Fragment" 100.00 124 100.00 100.00 4.06e-01 PDB 2OE4 "High Pressure Psuedo Wild Type T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 2OE7 "High-Pressure T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 2OE9 "High-Pressure Structure Of Pseudo-Wt T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 2OEA "High-Pressure Structure Of Pseudo-Wt T4 Lysozyme" 100.00 164 100.00 100.00 5.58e-01 PDB 2OU8 "Structure Of Spin-Labeled T4 Lysozyme Mutant T115r1 At Room Temperature" 100.00 164 100.00 100.00 5.82e-01 PDB 2OU9 "Structure Of Spin-Labeled T4 Lysozyme Mutant T115r1R119A" 100.00 164 100.00 100.00 5.70e-01 PDB 2Q9D "Structure Of Spin-Labeled T4 Lysozyme Mutant A41r1" 100.00 164 100.00 100.00 1.05e+00 PDB 2Q9E "Structure Of Spin-Labeled T4 Lysozyme Mutant S44r1" 100.00 164 100.00 100.00 6.06e-01 PDB 2RH1 "High Resolution Crystal Structure Of Human B2-Adrenergic G Protein- Coupled Receptor" 100.00 500 100.00 100.00 1.55e+00 PDB 3D4S "Cholesterol Bound Form Of Human Beta2 Adrenergic Receptor." 100.00 490 100.00 100.00 9.22e-01 PDB 3EML "The 2.6 A Crystal Structure Of A Human A2a Adenosine Receptor Bound To Zm241385." 100.00 488 100.00 100.00 1.64e+00 PDB 3G3V "Crystal Structure Of Spin Labeled T4 Lysozyme (V131r1) At 291 K" 100.00 164 100.00 100.00 1.06e+00 PDB 3G3W "Crystal Structure Of Spin Labeled T4 Lysozyme (T151r1) At 291 K" 100.00 164 100.00 100.00 5.82e-01 PDB 3G3X "Crystal Structure Of Spin Labeled T4 Lysozyme (T151r1) At 100 K" 100.00 164 100.00 100.00 5.82e-01 PDB 3JR6 "Sequential Reorganization Of Beta-Sheet Topology By Insertion Of A Single Strand" 100.00 170 100.00 100.00 1.27e+00 PDB 3K2R "Crystal Structure Of Spin Labeled T4 Lysozyme Mutant K65v1R76V1" 100.00 164 100.00 100.00 9.07e-01 PDB 3L2X "Crystal Structure Of Spin Labeled T4 Lysozyme Mutant 115-119rx" 100.00 164 100.00 100.00 9.26e-01 PDB 3L64 "T4 Lysozyme S44e/wt*" 100.00 164 100.00 100.00 5.70e-01 PDB 3NY8 "Crystal Structure Of The Human Beta2 Adrenergic Receptor In Complex With The Inverse Agonist Ici 118,551" 100.00 490 100.00 100.00 9.22e-01 PDB 3NY9 "Crystal Structure Of The Human Beta2 Adrenergic Receptor In Complex With A Novel Inverse Agonist" 100.00 490 100.00 100.00 9.22e-01 PDB 3NYA "Crystal Structure Of The Human Beta2 Adrenergic Receptor In Complex With The Neutral Antagonist Alprenolol" 100.00 490 100.00 100.00 9.22e-01 PDB 3ODU "The 2.5 A Structure Of The Cxcr4 Chemokine Receptor In Complex With Small Molecule Antagonist It1t" 100.00 502 100.00 100.00 4.39e-01 PDB 3OE0 "Crystal Structure Of The Cxcr4 Chemokine Receptor In Complex With A Cyclic Peptide Antagonist Cvx15" 100.00 499 100.00 100.00 4.38e-01 PDB 3OE6 "Crystal Structure Of The Cxcr4 Chemokine Receptor In Complex With A Small Molecule Antagonist It1t In I222 Spacegroup" 100.00 508 100.00 100.00 4.53e-01 PDB 3OE8 "Crystal Structure Of The Cxcr4 Chemokine Receptor In Complex With A Small Molecule Antagonist It1t In P1 Spacegroup" 100.00 502 100.00 100.00 4.39e-01 PDB 3OE9 "Crystal Structure Of The Chemokine Cxcr4 Receptor In Complex With A Small Molecule Antagonist It1t In P1 Spacegroup" 100.00 499 100.00 100.00 4.38e-01 PDB 3P0G "Structure Of A Nanobody-Stabilized Active State Of The Beta2 Adrenoceptor" 100.00 501 100.00 100.00 1.52e+00 PDB 3PBL "Structure Of The Human Dopamine D3 Receptor In Complex With Eticlopride" 100.00 481 100.00 100.00 7.29e-01 PDB 3PDS "Irreversible Agonist-Beta2 Adrenoceptor Complex" 100.00 458 100.00 100.00 1.07e+00 PDB 3QAK "Agonist Bound Structure Of The Human Adenosine A2a Receptor" 100.00 488 100.00 100.00 1.64e+00 PDB 3RUN "New Strategy To Analyze Structures Of Glycopeptide Antibiotic-Target Complexes" 100.00 168 100.00 100.00 5.66e-01 PDB 3RZE "Structure Of The Human Histamine H1 Receptor In Complex With Doxepin" 100.00 452 100.00 100.00 1.01e+00 PDB 3SB5 "Zn-Mediated Trimer Of T4 Lysozyme R125cE128C BY SYNTHETIC Symmetrization" 100.00 165 100.00 100.00 7.16e-01 PDB 3SB6 "Cu-Mediated Dimer Of T4 Lysozyme D61hK65HR76HR80H BY SYNTHETIC Symmetrization" 100.00 165 100.00 100.00 4.79e-01 PDB 3SB7 "Cu-Mediated Trimer Of T4 Lysozyme D61hK65HR76HR80H BY SYNTHETIC Symmetrization" 100.00 165 100.00 100.00 4.79e-01 PDB 3SB8 "Cu-Mediated Dimer Of T4 Lysozyme D61hK65H BY SYNTHETIC SYMMETRIZATION" 100.00 165 100.00 100.00 8.36e-01 PDB 3SB9 "Cu-Mediated Dimer Of T4 Lysozyme R76hR80H BY SYNTHETIC SYMMETRIZATION" 100.00 165 100.00 100.00 6.13e-01 PDB 3SBA "Zn-Mediated Hexamer Of T4 Lysozyme R76hR80H BY SYNTHETIC Symmetrization" 100.00 165 100.00 100.00 6.13e-01 PDB 3SBB "Disulphide-Mediated Tetramer Of T4 Lysozyme R76cR80C BY SYNTHETIC Symmetrization" 100.00 165 100.00 100.00 5.53e-01 PDB 3SN6 "Crystal Structure Of The Beta2 Adrenergic Receptor-Gs Protein Complex" 100.00 514 100.00 100.00 9.11e-01 PDB 3UON "Structure Of The Human M2 Muscarinic Acetylcholine Receptor Bound To An Antagonist" 100.00 467 100.00 100.00 7.71e-01 PDB 3V2W "Crystal Structure Of A Lipid G Protein-Coupled Receptor At 3.35a" 100.00 520 100.00 100.00 6.14e-01 PDB 3V2Y "Crystal Structure Of A Lipid G Protein-Coupled Receptor At 2.80a" 100.00 520 100.00 100.00 6.14e-01 PDB 3VW7 "Crystal Structure Of Human Protease-activated Receptor 1 (par1) Bound With Antagonist Vorapaxar At 2.2 Angstrom" 100.00 484 100.00 100.00 3.86e-01 PDB 4ARJ "Crystal Structure Of A Pesticin (translocation And Receptor Binding Domain) From Y. Pestis And T4-lysozyme Chimera" 100.00 339 100.00 100.00 6.12e-01 PDB 4DAJ "Structure Of The M3 Muscarinic Acetylcholine Receptor" 100.00 479 100.00 100.00 6.62e-01 PDB 4DJH "Structure Of The Human Kappa Opioid Receptor In Complex With Jdtic" 100.00 480 100.00 100.00 1.49e+00 PDB 4DKL "Crystal Structure Of The Mu-Opioid Receptor Bound To A Morphinan Antagonist" 100.00 464 100.00 100.00 7.06e-01 PDB 4EJ4 "Structure Of The Delta Opioid Receptor Bound To Naltrindole" 100.00 461 100.00 100.00 1.51e+00 PDB 4EXM "The Crystal Structure Of An Engineered Phage Lysin Containing The Binding Domain Of Pesticin And The Killing Domain Of T4-Lysoz" 100.00 347 100.00 100.00 5.07e-01 PDB 4GBR "N-terminal T4 Lysozyme Fusion Facilitates Crystallization Of A G Protein Coupled Receptor" 100.00 163 100.00 100.00 5.52e-01 PDB 4GRV "The Crystal Structure Of The Neurotensin Receptor Nts1 In Complex With Neurotensin (8-13)" 100.00 510 100.00 100.00 8.50e-01 PDB 4HTT "Crystal Structure Of Twin Arginine Translocase Receptor- Tatc In Ddm" 100.00 418 100.00 100.00 1.36e+00 PDB 4IAP "Crystal Structure Of Ph Domain Of Osh3 From Saccharomyces Cerevisiae" 100.00 260 100.00 100.00 8.34e-01 PDB 4LDE "Structure Of Beta2 Adrenoceptor Bound To Bi167107 And An Engineered Nanobody" 100.00 469 100.00 100.00 1.23e+00 PDB 4LDL "Structure Of Beta2 Adrenoceptor Bound To Hydroxybenzylisoproterenol And An Engineered Nanobody" 100.00 469 100.00 100.00 1.23e+00 PDB 4LDO "Structure Of Beta2 Adrenoceptor Bound To Adrenaline And An Engineered Nanobody" 100.00 469 100.00 100.00 1.23e+00 PDB 4OO9 "Structure Of The Human Class C Gpcr Metabotropic Glutamate Receptor 5 Transmembrane Domain In Complex With The Negative Alloste" 100.00 444 100.00 100.00 8.56e-01 PDB 4PHU "Crystal Structure Of Human Gpr40 Bound To Allosteric Agonist Tak-875" 100.00 491 100.00 100.00 5.17e-01 PDB 4PJZ "Crystal Structure Of T4 Lysozyme-gss-peptide In Complex With Teicoplanin-a2-2" 100.00 174 100.00 100.00 1.22e+00 PDB 4PK0 "Crystal Structure Of T4 Lysozyme-peptide In Complex With Teicoplanin- A2-2" 100.00 171 100.00 100.00 6.03e-01 PDB 4PLA "Crystal Structure Of Phosphatidyl Inositol 4-kinase Ii Alpha In Complex With Atp" 100.00 556 100.00 100.00 4.81e-01 PDB 4QKX "Structure Of Beta2 Adrenoceptor Bound To A Covalent Agonist And An Engineered Nanobody" 100.00 469 100.00 100.00 1.17e+00 PDB 4TN3 "Structure Of The Bbox-coiled-coil Region Of Rhesus Trim5alpha" 100.00 400 100.00 100.00 5.58e-01 PDB 4U15 "M3-mt4l Receptor Bound To Tiotropium" 100.00 418 100.00 100.00 6.45e-01 PDB 4U16 "M3-mt4l Receptor Bound To Nms" 100.00 418 100.00 100.00 6.45e-01 PDB 4W8F "Crystal Structure Of The Dynein Motor Domain In The Amppnp-bound State" 100.00 2661 100.00 100.00 5.05e-01 stop_ save_ #################### # Natural source # #################### save_natural_source _Saveframe_category natural_source loop_ _Mol_label _Organism_name_common _NCBI_taxonomy_ID _Superkingdom _Kingdom _Genus _Species $HELIX_E . . . . . . stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Saveframe_category experimental_source loop_ _Mol_label _Production_method _Host_organism_name_common _Genus _Species _Strain _Vector_name $HELIX_E 'chemical synthesis' . . . . . stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Saveframe_category sample _Sample_type solution _Details . loop_ _Mol_label _Concentration_value _Concentration_value_units _Concentration_min_value _Concentration_max_value _Isotopic_labeling $HELIX_E . mM 1 2 . TFE 50 % . . . H2O 45 % . . . D2O 5 % . . . stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _Saveframe_category NMR_spectrometer _Manufacturer unknown _Model unknown _Field_strength 0 _Details 'spectrometer information not available' save_ ############################# # NMR applied experiments # ############################# save_unknown_1 _Saveframe_category NMR_applied_experiment _Experiment_name unknown _Sample_label $sample_1 save_ save_NMR_spec_expt _Saveframe_category NMR_applied_experiment _Experiment_name unknown _BMRB_pulse_sequence_accession_number . _Details 'experiment information not available' save_ ####################### # Sample conditions # ####################### save_conditions_1 _Saveframe_category sample_conditions _Details . loop_ _Variable_type _Variable_value _Variable_value_error _Variable_value_units pH . . . temperature 288 0 K stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_referencing _Saveframe_category chemical_shift_reference _Details . loop_ _Mol_common_name _Atom_type _Atom_isotope_number _Atom_group _Chem_shift_units _Chem_shift_value _Reference_method _Reference_type _External_reference_sample_geometry _External_reference_location _External_reference_axis _Indirect_shift_ratio _Indirect_shift_ratio_citation_label _Correction_value_citation_label TSP H 1 'methyl protons' ppm 0.00 external direct . . . 1.0 $entry_citation $entry_citation stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_chem_shift_list_1 _Saveframe_category assigned_chemical_shifts _Details . loop_ _Experiment_label unknown stop_ loop_ _Sample_label $sample_1 stop_ _Sample_conditions_label $conditions_1 _Chem_shift_reference_set_label $chemical_shift_referencing _Mol_system_component_name 'fragment corresponding to Lys Helix E (residues 92-107)' _Text_data_format . _Text_data . loop_ _Atom_shift_assign_ID _Residue_author_seq_code _Residue_seq_code _Residue_label _Atom_name _Atom_type _Chem_shift_value _Chem_shift_value_error _Chem_shift_ambiguity_code 1 92 1 ASP HA H 4.30 . . 2 92 1 ASP HB2 H 3.09 . . 3 92 1 ASP HB3 H 2.99 . . 4 93 2 ALA H H 8.86 . . 5 93 2 ALA HA H 4.26 . . 6 93 2 ALA HB H 1.50 . . 7 94 3 VAL H H 7.77 . . 8 94 3 VAL HA H 3.84 . . 9 94 3 VAL HB H 2.16 . . 10 94 3 VAL HG1 H 1.06 . . 11 94 3 VAL HG2 H 0.99 . . 12 95 4 ARG H H 7.99 . . 13 95 4 ARG HA H 4.16 . . 14 95 4 ARG HB2 H 1.88 . . 15 95 4 ARG HG2 H 1.83 . . 16 95 4 ARG HG3 H 1.83 . . 17 95 4 ARG HD2 H 3.24 . . 18 95 4 ARG HD3 H 3.24 . . 19 95 4 ARG HH11 H 7.16 . . 20 95 4 ARG HH12 H 6.57 . . 21 96 5 ARG H H 7.94 . . 22 96 5 ARG HA H 4.07 . . 23 96 5 ARG HB2 H 1.91 . . 24 96 5 ARG HG2 H 1.78 . . 25 96 5 ARG HG3 H 1.68 . . 26 96 5 ARG HD2 H 3.24 . . 27 96 5 ARG HD3 H 3.24 . . 28 96 5 ARG HH11 N 7.16 . . 29 96 5 ARG HH12 N 6.57 . . 30 97 6 ALA H H 8.02 . . 31 97 6 ALA HA H 4.09 . . 32 97 6 ALA HB H 1.51 . . 33 98 7 ALA H H 8.08 . . 34 98 7 ALA HA H 4.16 . . 35 98 7 ALA HB H 1.55 . . 36 99 8 LEU H H 7.97 . . 37 99 8 LEU HA H 4.20 . . 38 99 8 LEU HB2 H 1.81 . . 39 99 8 LEU HG H 1.76 . . 40 99 8 LEU HD1 H 0.94 . . 41 100 9 ILE H H 8.19 . . 42 100 9 ILE HA H 3.72 . . 43 100 9 ILE HB H 1.92 . . 44 100 9 ILE HG13 H 1.19 . . 45 100 9 ILE HG2 H 0.91 . . 46 100 9 ILE HD1 H 0.87 . . 47 101 10 ASN H H 8.05 . . 48 101 10 ASN HA H 4.51 . . 49 101 10 ASN HB2 H 2.93 . . 50 101 10 ASN HB3 H 2.81 . . 51 101 10 ASN HD21 H 7.40 . . 52 101 10 ASN HD22 H 6.40 . . 53 102 11 MET H H 8.05 . . 54 102 11 MET HA H 4.24 . . 55 102 11 MET HB2 H 2.33 . . 56 102 11 MET HG2 H 2.72 . . 57 102 11 MET HG3 H 2.60 . . 58 103 12 VAL H H 8.34 . . 59 103 12 VAL HA H 3.70 . . 60 103 12 VAL HB H 2.16 . . 61 103 12 VAL HG1 H 1.04 . . 62 103 12 VAL HG2 H 0.78 . . 63 104 13 PHE H H 8.83 . . 64 104 13 PHE HA H 4.45 . . 65 104 13 PHE HB2 H 3.28 . . 66 104 13 PHE HB3 H 3.21 . . 67 104 13 PHE HD1 H 7.30 . . 68 104 13 PHE HD2 H 7.30 . . 69 104 13 PHE HE1 H 7.38 . . 70 104 13 PHE HE2 H 7.38 . . 71 104 13 PHE HZ H 7.34 . . 72 105 14 GLN H H 8.05 . . 73 105 14 GLN HA H 4.24 . . 74 105 14 GLN HB2 H 2.25 . . 75 105 14 GLN HG2 H 2.50 . . 76 105 14 GLN HG3 H 2.50 . . 77 105 14 GLN HE21 H 7.60 . . 78 105 14 GLN HE22 H 6.80 . . 79 106 15 MET H H 8.16 . . 80 106 15 MET HA H 4.50 . . 81 106 15 MET HB2 H 2.20 . . 82 106 15 MET HG2 H 2.77 . . 83 106 15 MET HG3 H 2.66 . . 84 107 16 GLY H H 7.80 . . 85 107 16 GLY HA2 H 4.00 . . stop_ save_