DDT Degradation

Description: DDT, or dichlorodiphenyltrichloroethane, is a synthetic pesticide which has been in existance since the 1800s, but its properties and uses were not discovered until the late 1930s. It is a very controversial compound because it has been found to be dangerous in animals, which have a hard time metabolizing DDT. In animals, it has a half-life between 6-8 years and resides in fatty tissues in the body.

There are several ways in which DDT is degradated. The first way is to remove a Cl group from the compound with an HCl leaving. This forms the compound DDE. The next way is by reductive chlorination to form DDD. The third way to degrade DDT is a longer process that branches into two pathways, but ultimately, both of the pathways lead to the formation of 4-chlorobenzoate.


Related BMRB Molecules

For complete information about pathway, see KEGG [map00351]